Non-coding RNAs as regulators in epigenetics

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Non-coding RNAs as regulators of gene expression and epigenetics.

Genome-wide studies have revealed that mammalian genomes are pervasively transcribed. This has led to the identification and isolation of novel classes of non-coding RNAs (ncRNAs) that influence gene expression by a variety of mechanisms. Here we review the characteristics and functions of regulatory ncRNAs in chromatin remodelling and at multiple levels of transcriptional and post-transcriptio...

متن کامل

SPOTLIGHT REVIEW Non-coding RNAs as regulators of gene expression and epigenetics

Genome-wide studies have revealed that mammalian genomes are pervasively transcribed. This has led to the identification and isolation of novel classes of non-coding RNAs (ncRNAs) that influence gene expression by a variety of mechanisms. Here we review the characteristics and functions of regulatory ncRNAs in chromatin remodelling and at multiple levels of transcriptional and post-transcriptio...

متن کامل

Non-Coding RNAs As Transcriptional Regulators In Eukaryotes

Non-coding RNAs up to 1,000 nucleotides in length are widespread in eukaryotes and fulfil various regulatory functions, in particular during chromatin remodeling and cell proliferation. These RNAs are not translated into proteins: thus, they are non-coding RNAs (ncRNAs). The present review describes the eukaryotic ncRNAs involved in transcription regulation, first and foremost, targeting RNA po...

متن کامل

Long Non-Coding RNAs as Master Regulators in Cardiovascular Diseases

Cardiovascular disease is the leading cause of death in the United States, accounting for nearly one in every seven deaths. Over the last decade, various targeted therapeutics have been introduced, but there has been no corresponding improvement in patient survival. Since the mortality rate of cardiovascular disease has not been significantly decreased, efforts have been made to understand the ...

متن کامل

Long non-coding RNAs as key regulators of cancer metastasis

Long non-coding RNAs as key regulators of cancer metastasis Pratirodh Koirala1, De-Hong Zou2, Yin-Yuan Mo1,3 1Department of Biochemistry and Cancer Institute, University of Mississippi Medical Center, Jackson, MS 39201, USA. 2Department of Breast Surgery, Zhejiang Cancer Hospital, Hangzhou 310022, China. 3Department of Pharmacology/Toxicology, University of Mississippi Medical Center, Jackson, ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Oncology Reports

سال: 2016

ISSN: 1021-335X,1791-2431

DOI: 10.3892/or.2016.5236